Bu brings more than 30 years of experience in neurodegenerative disease research in top academic institutions at Washington University in St. Louis and Mayo Clinic. He has published over 300 articles and is regarded as a leader in the field of Alzheimer’s disease and related dementias with specific expertise in protein aggregation, immune responses, and cerebrovascular function. His landmark work in addressing the pathobiology of APOE and TREM2, two strong genetic risk factors for Alzheimer’s disease, has led to multiple fundamental discoveries and disease insights. Prior to joining SciNeuro, Bu was an endowed professor and chair of Department of Neuroscience at Mayo Clinic. His accomplishments were recognized by multiple awards in US including the MetLife Foundation Award for Medical Research in Alzheimer’s disease and as a Fellow of American Association for the Advancement of Science (AAAS). Bu is the co-founder and Editor-in-Chief of Molecular Neurodegeneration, a member of the advisory board of Neuron, and an Associate Editor of Science Advances.